We are a biomedical technology start-up company focused on commercializing quantitative sensory testing (QST) technologies developed at the University of Michigan. We also provide custom hardware and software solutions for research. We were founded in 2013, in Ann Arbor, Michigan.
Provide state-of-the-art QST technologies and engineering support for the conceptualization, design, and fabrication of custom medical systems to physicians and biomedical researchers.
Multimodal Automated Sensory Testing (MAST) system
A point-of-care QST platform developed at the University of Michigan by Drs. Harte, Clauw, and Kruger to measure threshold and suprathreshold pain sensitivity easily and accurately in clinical studies. It applies computer-controlled pressure stimuli to the thumbnail bed and records resulting perceptual responses. The system consists of a wirelessly connected control notebook, a touchscreen tablet for participant feedback, and battery-powered handheld stimulator.
A computer-controlled, MRI-compatible pressure pain stimulator. The system coordinates a programmed sequence of stimuli in synchronization with the imaging sequence. It is compatible with all MRI brands and models, and its integration with E-prime or other presentation software provides instructions, visual cues, and/or collection of participant feedback during testing. The system consists of a control computer, pneumatic pressure generator, and a MRI-compatible thumbnail pressure stimulator (custom stimulators for other body sites also available).
A lightweight hot water foot bath. The programmable thermal circulator maintains circulating water temperatures between 25-50°C. The custom designed foot rest permits water flow over top and bottom foot surface. Ideal as a conditioning stimulus in conditioned pain modulation (CPM) studies.
Our technologies have been used in a number of research studies:
Landis JR, Williams DA, Lucia MA, Clauw DJ, Naliboff BD, et al., and MAPP Research Network Study Group. (2014). The MAPP research network: design, patient characterization and operations. BMC Urol 14: 58.
Yang CC, Weinfurt KP, Merion RM, Kirkali Z, et al. (2016). The symptoms of lower urinary tract dysfunction research network. J Urol 196: 146-52. PMID: 26784646
Wasserman R, Hassett A, Harte SE, Gosling J, Malinoff HL, Berland DW, Zollars J, Moser SE, Brummett C. (2015). Pressure pain sensitivity in patients with suspected opioid-induced hyperalgesia. Region Anesth Pain M 40:687-93. PMID: 26469365
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Our technologies are also being used for research by a number of institutions:
Services We Offer
Grant Kruger, Ph.D.
Co-Founder – Engineering
Dr Kruger received his doctorate in Electrical Engineering: Intelligent Manufacturing Systems in 2006, while also working as a lecturer in Mechatronic Systems. In 2007 he joined the S.M. Wu Manufacturing Research Center, as a scientist, in the Mechanical Engineering Department at the University of Michigan. For the last 10-years he has performed research in biomedical information systems. His expertise encompasses manufacturing, physiologic monitoring, robotics, ultrasound, embedded systems, signal and image processing and prototype manufacturing.
Steven Harte, Ph.D.
Co-Founder – Neuroscience
Dr. Harte is neuroscientist with over twenty years of experience studying sensory physiology, affect, and pain measurement. He currently serves as Director of Sensory Science at the University of Michigan Chronic Pain and Fatigue Research Center within the Department of Anesthesiology.
Paul Luzynski, B.H.A.
Paul Luzynski is a practice manager for The Villages Health, a multi-specialty health care system, located in The Villages, FL. The Villages Health provides primary and specialty care to residents of The Villages and the surrounding areas. The Villages is the largest retirement community in the U.S with a population of over 125,000 residents. Paul obtained his bachelor’s degree in Health Services Administration from the University of Central Florida. He is originally from Michigan, but has called central Florida home for the past 15 years.
Sam Kruger, B.B.A.
Sam Kruger obtained a Bachelors in Business Administration from Eastern Michigan University in 2017 after moving to Ann Arbor from sunny South Africa in 2007. During her studies she obtained valuable management and administration experience by working part-time in the optical industry. She is passionate about marketing and customer experience, and her organizational skills and detail-oriented nature support her strong management focus.